Disease: secondary acute myeloid leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
THPO P40225 thrombopoietin 0.20 0.513 0.692
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TBX22 Q9Y458 T-box transcription factor 22 Transcription factor 0.98 0.603 0.577
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SEPTIN6 Q14141 septin 6 Enzyme modulator 0.93 0.644 0.385
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
EBP Q15125 EBP cholestenol delta-isomerase Enzyme 0.94 0.494 0.846